Page 8 - Clinical Connections - Autumn 2024

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Page 8 - Clinical Connections - Autumn 2024
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ºÚÁÏÉç RESEARCH    STUDY    VETERINARY SERVICES       ºÚÁÏÉç.AC.UK
           Exotics Referrals
          APPENDICITIS – UNDERDIAGNOSED IN


          RABBITS?

          Joanna Hedley, Senior Lecturer in Exotic Species and Small Mammal Medicine and Surgery

                ut   stasis   or   ‘gastrointestinal   Dental changes, arthritis and spondylosis   abdominal ultrasound, the amount of gas
                syndrome’ is one of the most   are  common  causes  of  pain  which  may   present in rabbits with gut stasis may limit
         G common reasons for rabbits to     be diagnosed with radiography once   definitive diagnosis in some cases. This is
          be presented to the ºÚÁÏÉç Exotics Referral   changes are moderate-advanced, but often   where we find CT scans to be an invaluable
          Service.                           appreciated at a much earlier stage on CT   diagnostic tool, as dilation of the appendix
           While  a  rabbit  with  uncomplicated   scan.                         and thickening of the sacculus rotundus
          gut stasis can usually be managed    Once underlying causes like these are   can be quickly visualised, allowing speedy
          symptomatically  in  first  opinion  practice,   identified  and  treated,  gut  stasis  episodes   treatment.
          many of the cases we see are more critical   can often be resolved. However the more
          patients,  often  requiring  intensive  care  in   CT scans performed in these cases,
          hospital with us.                  the  more  we  are  finding  not  just  these
           We also see patients who are having   common causes of gut stasis but also some
          recurrent bouts of stasis with no obvious   unexpected findings.
          trigger.
           The initial approach to any rabbit with gut   Important differential
          stasis always starts with stabilisation, often   In recent years, appendicitis with associated
          including active warming, intravenous fluid   sacculitis has been recognised as an
          therapy,  nutritional  support,  analgesia  and   important  differential  for  gut  stasis  +/-
          prokinetics as required. Once treatment has   abdominal pain, inappetence and weight
          been initiated, the focus can then move onto   loss in rabbits.
          identifying the underlying cause.    As a prey species, the presence and
                                             degree of pain in rabbits can be hard to
          Diagnostic approaches              assess,  as they will naturally  hide any
          The diagnostic approach will depend on   signs  of weakness  from us,  the  predator
          whether the signs are thought to be primarily   species. Appendicitis cases can, therefore,
          due to gastrointestinal disease or secondary   often be chronic with rabbits just presenting
          to  pain  elsewhere,  stress  or  systemic   with a prolonged non-resolving gut stasis
          disease.                           episode or recurrent signs, despite standard   Bluey, who was treated by the ºÚÁÏÉç Exotics
           Bloodwork,  full  dental  examination  supportive treatment.           Referral Service
          under sedation and initial imaging – such   Some cases provide more obvious clues,
          as radiography – can be easily performed   such as pyrexia or haematological changes,   In the literature, a mix of medical and
          in-house. However in many of the more   but this is not always the case. In fact, some   surgical treatment is described and surgical
          challenging  cases,  we  have  found  cases may actually present hypothermic   treatment has been suggested to carry a
          advanced  imaging  to  be  increasingly   instead  and  co-morbidities  are  not  better  prognosis.  However  the  majority  of
          helpful, specifically to identify any focus of   uncommon, which can confuse diagnosis.   cases that we have seen have been rabbits
          pain or structural abnormality, which may be   While changes in the appendix and   with recurrent gut stasis episodes, rather
          resulting in the gut stasis signs.   sacculus rotundus may be visualised on   than critical cases requiring appendectomy.
                                                                                   These more chronic cases, in our
                                                                                 experience,  have  responded  extremely
                                                                                 well to medical treatment with antibiotics, in
                                                                                 addition to the normal supportive treatment
                                                                                 given to our gut stasis patients.
                                                                                   We   therefore  strongly  recommend
                                                                                 considering appendicitis and sacculitis
                                                                                 as  a  differential  for  these  patients  –  and
                                                                                 advanced imaging for diagnosis, when
                                                                                 required, as it can make a real difference to
                                                                                 resolving these more challenging cases.


           CT image of Bluey: The caecal wall (CYAN callipers) is diffusely thickened (2-3mm, normal 1.2
           +/- 0.1mm) and diffusely contains gas foci. In the caecal lumen there is a moderate amount of gas
           and faecal contents. Colonic contents are hyperdense but formed. The colon wall is normal. Jejunal
           lymph nodes are prominent (4.8mm thick) but enhance normally                  For the ºÚÁÏÉç Exotics and Small Mammals
                                                                                       Service, please call: 020 7554 3528
                                                                                         Email:
                                                                                       londonreferrals@rvc.ac.uk


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