Page 11 - Clinical Connections - Spring 2023

 

 

 

 

 

Page 11 - Clinical Connections - Spring 2023
P. 11

Research News






        ROTTWEILERS - GREATEST              MOST COMMON DISEASES                IONISED HYPERCALCAEMIA
        RISK OF CRANIAL CRUCIATE  IN PET CATS REVEALED                          IN CATS AND CONCURRENT
        LIGAMENT RUPTURE                                                        UROLITHIASIS
                                             VetCompass research has revealed
        A VetCompass study has explored factors   what are the most common disorders   VetCompass  research  has  explored
        for cranial cruciate ligament (CCL) rupture in   diagnosed by veterinary surgeons in cats   the diagnoses associated with ionised
        dogs and how it is managed. The research   across the UK. Overall health patterns were   hypercalcaemia in cats and the prevalence
        also identifies which breeds are most at risk.  reported from a random sample of 18,249   of  concurrent  urolithiasis  among  cats
          The  research  findings  will  help  owners   cats from a study population of 1,255,130.  referred to the QMHA.
        and vets identify dogs at most risk of   On average, each cat was diagnosed   The study involved both Queen Mother
        CCL rupture and highlight the clinical   with one condition per year.  The most   Hospital Animals Internal Medicine Service
        rationales  used  in  first  opinion  practice  to   common  disorders  were  gum  disease   and  the  VetCompass  team.  The  research
        decide between surgical and non-surgical   (15.23%), obesity (11.58%), general dental   covers the largest group of cats with ionised
        management.                         disease (9.23%), overgrown nails (5.23%),   hypercalcaemia yet reported in the literature.
          The study included 1,000 CCL rupture   flea infestation (5.07%) and heart murmur   A  defined  pathological  cause  for
        cases and a random selection of 500,000   (4.44%). Risks for  these conditions varied   hypercalcaemia  was  identified  in  just
        other dogs without CCL injury. The breeds   widely between ages and sex.  Average   over half of the 238 cats with ionised
        at most risk of CCL rupture, compared with   annual disorder count was higher in males   hypercalcaemia,  with  acute  kidney injury
        crossbreeds, were Rottweiler (x 3.66 times   than females, and higher in older cats than   (13%  of  cases),  malignancy  associated
        risk),  bichon frisé  (x  2.09),  West  Highland   younger cats         (10.1%),  idiopathic  hypercalcaemia
        white terrier (x 1.80) and golden retriever (x   Females  and  males  had  different  risk   (10.1%)  and  chronic  kidney  disease/renal
        1.69). The breeds with the lowest risk were   for almost half of the 30 most common   diet associated (8.4%) the most common
        cockapoo (x  0.26),  Chihuahua  (x 0.31),   conditions. For example, female cats had   diagnoses. Only 2% of cats were diagnosed
        shih-tzu (x 0.41) and German shepherd dog   higher risk than males for poor quality of   with primary hyperparathyroidism or a toxic
        (x 0.43).                           life,  post-operative  wound  complication,   cause.
                                        Common disorders in cats
          Factors affecting opting for surgery or not   over-grooming,  flea  bite  hypersensitivity,   Urolithiasis  was  identified  in  83.3%
        had not previously been epidemiologically   hyperthyroidism,  and  overgrown  nail(s).   of  acute  kidney  injury  associated
                                        Cats are popular companion animals in the UK. The human-animal bond shared
                                        between cats and their owners can be beneficial to both people and cats. To ensure
                                        a good quality of life for their cats, it is important for owners to understand which
        analysed. Insured dogs and dogs weighing   Males had higher risk for periodontal   hypercalcaemia,  72.7%  of  iatrogenic
                                        medical conditions may commonly affect their pets so they can take a proactive role
                                        in the healthcare of their cats.
        over 20kg were more likely to receive surgical   disease,  road  traffic  accidents,  heart   hypercalcaemia, 61.1% of CKD/renal diet-
                                        This study aimed to identify the most common disorders diagnosed in cats in the UK
                                        and explore how aging and male/female status affected these. This information can
        management, while dogs older than nine   murmur, lameness, obesity, abscess wound   associated hypercalcaemia and 50% of
                                        help owners take a more informed role in caring for their cats and help veterinary
                                        teams to focus on targetted preventative healthcare.
                                                          Total number of
        years and those concurrently experiencing   and cat bite injuries.  Average age of cats in   idiopathic hypercalcaemia cases that were
                                                                        the study
                                                          cats in the study
        another major clinical problem were less   The  study  findings  provide  vets,  vet   imaged (<50% for other diagnoses).
                                                            A random
                                                            sample of
        likely to receive surgical management.  nurses, breeders and owners with new   The proportion of ionised hypercalcaemic
                                                          18,249 cats
                                                                        5.67
                                                                        years
                                            evidence to better understand and predict   cats  with  concurrent urolithiasis highlights
                                                           from an overall
                                                           population of
                                                           1, 255,130 cats in
          Other key findings include:       the disorder occurrence.            the need for further studies into calcium-
                                                           VetCompass

                                                                                based urolith formation, especially as these
          •  The  average  age  at  first  diagnosis  of         Most common cat breeds  uroliths were incidentally detected in many
            CCL rupture was 7.4 years                                           of these cats with idiopathic hypercalcaemia.
                                             British Short Hair (3.01%) was the most common cat breed in the UK,
          •  Dogs aged 6 to < 9 years had the   followed by Ragdoll (1.82%) and Bengal (1.22%). Other common breeds   These  results  help  highlight  the  more
                                              included Maine Coon (0.93%), Persian (0.73%) and Siamese (0.68%).
            greatest risk (x 3.24) of CCL rupture                               common diagnoses associated with ionised
            diagnosis compared  with dogs  <  3   British Short Hair  cats (moggies)   hypercalcaemia in cats, emphasising that
                                                                     Crossbreed
                                                                     represented
            years                                                    87.98% of cats   the  three  most  likely  aetiologies  include
          •  Dogs weighing more than 30kg (x 2.19)                   in the study.   kidney-related causes, neoplasia and
            and insured (x 2.79) were most likely to              Bengal        idiopathic hypercalcaemia.
            have surgery                    Ragdoll
          •  Dogs over 12 years (x 0.26) and with a                                Research paper: Broughton et al. (2023) ‘Ionized
            comorbidity (x 0.38) were least likely to                                 hypercalcemia in 238 cats from a referral hospital
            have surgery                                                        population (2009-2019)’, Journal of Veterinary Internal
                                                                                Medicine
                                                Most common cat disorders
            Research paper: C. Pegram et al. (2023) ‘Risk   Research paper: O’Neill et al. (2023) ‘Commonly
                                                diagnosed disorders in domestic cats in the UK,
            factors for unilateral cranial cruciate ligament   Most common specific disorders diagnosed in cats in the UK
        rupture diagnosis and for clinical management in dogs   and their associations with sex and age’, Journal of
        under primary veterinary care in the UK’, The Veterinary   Feline Medicine and Surgery   Periodontal disease
        Journal                                                 Obesity
                                                Non-specified dental disease  average
                                          Specific disorders  Heart murmur  disorder. The average
                                                                     The
                                              Overgrown nail(s)
                                                                  disorder count
                                               Flea infestation
                                                                  per year was one
                                                                 annual disorder count
                                                                 was higher in males
                                              Weight loss
                                                                 than females, and
                                                                 higher in older cats
                                              Vomiting
                                                                   than younger
                                                                    cats.
                                              Abscess
                                             Diarrhoea
                                           0   2    4   6   8   10  12   14  16
                                                     Percentage of cats affected (%)                    Spring 2023   11
                                             Most common cat disorder groups
                                            Most common disorder groups diagnosed in cats in the UK
                                                                     Dental disorder
                                                          Obesity
                                                     Skin disorder
                                                   Enteropathy
                                           Disorder groups  Parasite infestation
                                               Heart disease
                                             Traumatic injury
                                            Claw/nail disorder
                                            Thin/underweight
                                             Eye disorder
                                           0  2  4   6  8  10  12  14  16  18  20  22
                                                      Percentage of cats affected (%)
                                               Female cats had higher
                                              frequency than males for six
                                                specific disorders:
                                               •  poor quality of life   Male cats had higher
                                              •   post-operative wound   frequency than females for
                                                 complication   eight specific disorders:
                                                •   over-grooming   •  periodontal disease
                                              •  flea bite hypersensitivity  •   road traffic accident (RTA)
                                               •  overgrown nail(s)  •   heart murmur
                                               •   hyperthyroidism  •   lameness
                                                                 •  obesity
                                                                 •  abscess
                                                                 •   wound
                                                                •  cat bite injury
                                          Younger cats (under 8 years) had higher frequency than older cats for four disorders:
                                             cat bite injury, flea infestation, road traffic accident and post-operative wound
                                             complication. Older cats (over 8 years) had higher frequency for 23 disorders.
                                                        Conclusions
                                            Several                      These
                                           disorders were             results can assist
                                         noted with differential   The high frequency of   veterinarians, veterinary
                                         risk by age and male/  potentially preventable   nurses, cat breeders and
                                         female, suggesting some   disorders such as dental   cat owners by providing an
                                        useful welfare opportunities   disease and obesity suggests the   evidence base to understand
                                        for veterinary professionals   value of improved veterinary   and predict disorder
                                        to target tailored veterinary   communication and education   occurrence, and to identify
                                        care to specific higher risk   of cat-owners.  key health and welfare
                                           groups of cats.           opportunities for their
                                                                         cats.
                                                    CLICK TO READ THE FULL STUDY
                                       O’Neill et al. (2023) “Commonly diagnosed disorders in domestic cats in the UK, and their associations with sex and age”, Journal of Feline Medicine and Surgery,
                                                        DOI: 10.1177/1098612X231155016
                                        VetCompass /vetcompass carries out welfare research based on anonymised clinical information shared from over 30%
                                         of UK veterinary practices. We are very grateful to the owners and veterinary professionals who contribute to VetCompass research.
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