ºÚÁÏÉç

Professor Lloyd’s research interests are focused on cutaneous infection and immune responses in companion and farm animals with special interest in colonisation, transmission and pathogenesis of infection by staphylococci, including the emergence of methicillin-resistant Staphylococcus aureus in domestic animals, antimicrobial resistance and yeasts of the genus Malassezia.

LAPPIN, M. R., BLONDEAU, J. M., BOOTHE, D., BREITSCHWERT, E. B., GUARDABASSI, L, LLOYD, D. H., PAPICH, M. G., RENKIN, S. C., SYKES, J. E., TURNIDGE, J., WEESE, J. S. (2017) Antimicrobial use guidelines for treatment of respiratory tract disease in dogs and cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases. J Vet Int Med. 31, 279-294. PMID: 28185306.

BROWNE, C, LOEFFLER, A, HOLT, H. R., CHANG, Y. M., LLOYD, D. H, NEVEL, M. (2017) Low temperature and dust favour in vitro survival of Mycoplasma hyopneumoniae: time to revisit indirect transmission in pig housing. Letters Appl Microbiol. 64, 2-7. PMID: 27759918.

FOUNTAIN, K. I., STEVENS, K. B., LLOYD, D. H., LOEFFLER, A. (2017) Skin disease in captive bats: results of an online survey of zoos and rehabilitators in Europe, North America and Australasia. Vet Dermatol. 28, 219-e52. PMID: 28044386.

McCARTHY, A. J., HARRISON, E. M., STANKZAC-MROZEK, K., LEGGETT, B., WALLER, A., HOLMES, M. A., LLOYD, D. H., LINDSAY, J. A., LOEFFLER, A. (2015) Genomic insights into the rapid emergence and evolution of multidrug-resistance in Staphylococcus pseudintermedius. J Antimicrob Chemother 70, 997-1007. PMID: 25527273.

GOH, S., LOEFFLER, A., LLOYD, D. H., NAIR, S.P., GOOD, L. (2015) Oxacillin sensitization of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius by antisense peptide nucleic acids in vitro. BMC Microbiol.15, 262. PubMed ID 26560174.

BEEVER, L., BOND, R., GRAHAM, P. A., JACKSON, B., LLOYD, D.H., LOEFFLER, A. (2015) Increasing antimicrobial resistance in clinical isolates of Staphylococcus intermedius group bacteria and emergence of MRSP in the UK. Vet Rec. 176, 172.  PubMed ID: 25376505.

McCARTHY, A. J., LOEFFLER, A., WITNEY, A. A., GOULD, K. A., LLOYD, D. H., LINDSAY, J. A. (2014) Extensive horizontal gene transfer during Staphylococcus aureus co-colonization in vivo. Genome Biol Evol. 6, 2697-708. PubMed ID: 25260585.

HILLIER, A., LLOYD, D. H., WEESE, J. S,, BLONDEAU, J. M., BOOTHE, D., BREITSCHWERDT, E., GUARDABASSI, L., PAPICH, M. G., RANKIN, S., TURNIDGE, J. D., SYKES, J. E. (2014) Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis (Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases). Vet Dermatol. 25, 163-75. PubMed ID: 24720433.

LEHNER, G., LINEK, M., BOND, R., LLOYD, D. H., PRENGER-BERNINGHOFF, E., THOM, N., STRAUB, I., VERHAYEN, K., LOEFFLER, A.. (2014) Case-control risk factor study of methicillin-resistant Staphylococcus pseudintermedius (MRSP) infection in dogs and cats in Germany. Vet
Microbiol. 168, 154-60. PubMed ID: 24290489.

LOEFFLER, A., McCARTHY, A., LLOYD, D. H., MUSILOVA, E., PFEIFFER, D. U., LINDSAY, J. A. (2013) Whole-genome comparison of meticillin-resistant Staphylococcus aureus CC22 SCCmecIV from people and their in-contact pets. Vet Dermatol. 24, 538-e128. PubMed ID:
23869430.

PORPHYRE, T., GIOTIS, E. S., LLOYD, D. H., STARK, K. D.. (2012) A metapopulation model to assess the capacity of spread of meticillin-resistant Staphylococcus aureus ST398 in humans. PLoS One. 7, e47504. PubMed ID: PMC3480390.

GIOTIS, E. S., LOEFFELR, A., KNIGHT-JONES, T., LLOYD, D. H. (2012) Development of a skin colonization model in gnotobiotic piglets for the study of the microbial ecology of meticillin-resistant Staphylococcus aureus ST398. J Appl Microbiol. 113, 992-1000. PubMed ID: 22805003.

LLOYD, D. H. (2012) Alternatives to conventional antimicrobial drugs: a review of future prospects. Vet Dermatol. 23, 299-304, PubMed ID: 22409347.

LOEFFLER, A., PFEIFFER, D. U., LINDSAY, J. A., SOARES-MAGALHAES, R. J., LLOYD,  D. H. (2011) Prevalence of and risk factors for MRSA carriage in companion animals: a survey of dogs, cats and horses. Epidemiol Infect. 139, 1019-28. PubMed ID: 20943000.

LOEFFLER, A., PFEIFFER, D. U., LLOYD, D. H., SMITH, H., SOARES-MAGALHAES, R., LINDSAY, J.A. (2010) Meticillin-resistant Staphylococcus aureus carriage in UK veterinary staff and owners of infected pets: new risk groups. J Hosp Infect. 74, 282-8. PubMed ID: 20080322.

LOEFFLER, A., KEARNS, A. M., ELLINGTON, M. J., SMITH, L. J., UNT, V. E., LINDSAY, J. A/, PFEIFFER, D. U., LLOYD, D. H. (2009) First isolation of MRSA ST398 from UK animals: a new challenge for infection control teams? J Hosp Infect. 2009 72, 269-71. PubMed ID: 19481297.

SUNG, J. M., LLOYD, D. H. & LINDSAY, J. A. (2008) Staphylococcus aureus host specificity: comparative genomics of human versus animal isolates by multi-strain microarray. Microbiology 154, 1949-1959.

LOEFFLER, A., LINEK, M., MOODLEY, A., GUARDABASSI, L., SUNG, J. M., WINKLER, M., WEISS, R. & LLOYD, D. H. (2007) First report of multiresistant, mecA-positive Staphylococcus intermedius in Europe: 12 cases from a veterinary dermatology referral clinic in Germany. Vet Dermatol 18, 412-421.

LLOYD, D. H., VIAC, J., WERLING, D., REME, C. A. & GATTO, H. (2007) Role of sugars in surface microbe-host interactions and immune reaction modulation. Vet Dermatol 18, 197-204.

CERUNDOLO, R., LLOYD, D. H., VAESSEN, M. M., MOL, J. A., KOOISTRA, H. S. & RIJNBERK, A. (2007) Alopecia in pomeranians and miniature poodles in association with high urinary corticoid:creatinine ratios and resistance to glucocorticoid feedback. Vet Rec 160, 393-397.

SUNG, J. M., CHANTLER, P. D. & LLOYD, D. H. (2006) Accessory gene regulator locus of Staphylococcus intermedius. Infect Immun 74, 2947-2956.

MOODLEY, A., STEGGER, M., BAGCIGIL, A. F., BAPTISTE, K. E., LOEFFLER, A., LLOYD, D. H., WILLIAMS, N. J., LEONARD, N., ABBOTT, Y., SKOV, R. & GUARDABASSI, L. (2006) spa typing of methicillin-resistant Staphylococcus aureus isolated from domestic animals and veterinary staff in the UK and Ireland. J Antimicrob Chemother 58, 1118-1123.

LOEFFLER, A., SOARES-MAGALHAES, R., BOND, R. & LLOYD, D. H. (2006) A retrospective analysis of case series using home-prepared and chicken hydrolysate diets in the diagnosis of adverse food reactions in 181 pruritic dogs. Vet Dermatol 17, 273-279.

LITTLER, R. M., BATT, R. M. & LLOYD, D. H. (2006) Total and relative deficiency of gut mucosal IgA in German shepherd dogs demonstrated by faecal analysis. Vet Rec 158, 334-341.

CURTIS, C. F., LAMPORT, A. I. & LLOYD, D. H. (2006) Masked, controlled study to investigate the efficacy of a Staphylococcus intermedius autogenous bacterin for the control of canine idiopathic recurrent superficial pyoderma. Vet Dermatol 17, 163-168.

BOND, R., PATTERSON-KANE, J. C., PERRINS, N. & LLOYD, D. H. (2006) Patch test responses to Malassezia pachydermatis in healthy basset hounds and in basset hounds with Malassezia dermatitis. Med Mycol 44, 419-427.

BOND, R., HABIBAH, A., PATTERSON-KANE, J. C. & LLOYD, D. H. (2006) Patch test responses to Malassezia pachydermatis in healthy dogs. Med Mycol 44, 175-184.

PFEIFFER, D., LLOYD, D., LOEFFLER, A., SOARES-MAGALHAES, R., RICH, M., ROBERTS, L. & LINDSAY, J. (2005) Investigation of MRSA in small animal practice. Vet Rec 157, 179-180.

LOEFFLER, A., BOAG, A. K., SUNG, J., LINDSAY, J. A., GUARDABASSI, L., DALSGAARD, A., SMITH, H., STEVENS, K. B. & LLOYD, D. H. (2005) Prevalence of methicillin-resistant Staphylococcus aureus among staff and pets in a small animal referral hospital in the UK. J Antimicrob Chemother 56, 692-697.

LEONE, F., CERUNDOLO, R., VERCELLI, A. & LLOYD, D. H. (2005) The use of trilostane for the treatment of alopecia X in Alaskan malamutes. J Am Anim Hosp Assoc 41, 336-342.

LOEFFLER, A., LLOYD, D. H., BOND, R., KIM, J. Y. & PFEIFFER, D. U. (2004) Dietary trials with a commercial chicken hydrolysate diet in 63 pruritic dogs. Vet Rec 154, 519-522.

GUARDABASSI, L., SCHWARZ, S. & LLOYD, D. H. (2004) Pet animals as reservoirs of antimicrobial-resistant bacteria. J Antimicrob Chemother 54, 321-332.

CERUNDOLO, R., LLOYD, D. H., PERSECHINO, A., EVANS, H. & CAUVIN, A. (2004) Treatment of canine Alopecia X with trilostane. Vet Dermatol 15, 285-293.

BOND, R., PATTERSON-KANE, J. C. & LLOYD, D. H. (2004) Clinical, histopathological and immunological effects of exposure of canine skin to Malassezia pachydermatis. Med Mycol 42, 165-175.

SAIJONMAA-KOULUMIES, L. E., MYLLYS, V. & LLOYD, D. H. (2003) Diversity and stability of the Staphylococcus intermedius flora in three bitches and their puppies. Epidemiol Infect 131, 931-937.

SAIJONMAA-KOULUMIES, L. E. & LLOYD, D. H. (2002) Colonization of neonatal puppies by Staphylococcus intermedius. Vet Dermatol 13, 123-130.

SAIJONMAA-KOULUMIES, L. E. & LLOYD, D. H. (2002) Adherence of Staphylococcus intermedius to canine corneocytes in vitro. Vet Dermatol 13, 169-176.

PATEL, A., LLOYD, D. H., HOWELL, S. A. & NOBLE, W. C. (2002) Investigation into the potential pathogenicity of Staphylococcus felis in a cat. Vet Rec 150, 668-669.

HENDRICKS, A., SCHUBERTH, H. J., SCHUELER, K. & LLOYD, D. H. (2002) Frequency of superantigen-producing Staphylococcus intermedius isolates from canine pyoderma and proliferation-inducing potential of superantigens in dogs. Res Vet Sci 73, 273-277.

BOND, R., PATTERSON-KANE, J. C. & LLOYD, D. H. (2002) Intradermal test reactivity to Malassezia pachydermatis in healthy basset hounds and basset hounds with Malassezia dermatitis. Vet Rec 151, 105-109.

BOND, R. & LLOYD, D. H. (2002) Immunoglobulin G responses to Malassezia pachydermatis in healthy dogs and dogs with Malassezia dermatitis. Vet Rec 150, 509-512.

BOND, R., CURTIS, C. F., HENDRICKS, A., FERGUSON, E. A. & LLOYD, D. H. (2002) Intradermal test reactivity to Malassezia pachydermatis in atopic dogs. Vet Rec 150, 448-449.

STURGEON, C., LAMPORT, A. I., LLOYD, D. H. & MUIR, P. (2000) Bacterial contamination of suction tips used during surgical procedures performed on dogs and cats. Am J Vet Res 61, 779-783.

BOND, R., WREN, L. & LLOYD, D. H. (2000) Adherence of Malassezia pachydermatis and Malassezia sympodialis to canine, feline and human corneocytes in vitro. Vet Rec 147, 454-455.

BOND, R., LAMPORT, A. I. & LLOYD, D. H. (2000) Colonisation status of Malassezia pachydermatis on the hair and in the hair follicle of healthy beagle dogs. Res Vet Sci 68, 291-293.

David is no longer involved in regular teaching in the undergraduate course but continues to teach postgraduates including Masters' degree and PhD students within his areas of special interest.

David is no longer directly involved in clinical referral caswork at the ºÚÁÏÉç.